Method of selectively destroying neoplastic cells

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424 931, 424 9321, 4351723, 4352401, 4352402, 43524025, 4353201, A61K 4800, C12N 500, C12N 1500, C07N 1400

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active

056887736

ABSTRACT:
A method for selectively killing nervous system and peripheral neoplastic cells is provided. Viral vectors are used to selectively express a cytochrome P450 gene in neoplastic cells, whose gene product targets the cells for selective killing, by rendering the cells sensitive to a chemotherapeutic agent.

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