Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving viable micro-organism
Reexamination Certificate
2005-05-31
2005-05-31
Smith, Lynette R. F. (Department: 1645)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving viable micro-organism
C210S222000, C210S515000, C210S520000, C210S695000, C365S039000, C424S001210, C435S002000, C435S007200, C435S007210, C435S007230, C435S007240, C435S029000, C435S030000, C435S173900, C435S174000, C435S176000, C435S177000, C435S182000, C435S183000
Reexamination Certificate
active
06900029
ABSTRACT:
A separation procedure for separating a selected desired or undesired population from a biological sample utilizing relatively heavy, dense particles and gravity sedimentation. The particles have one or more reactants bound thereto which are specific to and will bind with the selected population. The particles preferably are mixed with the sample by repeatedly causing the particles to settle through a substantial portion of the sample to bind to the selected population. The particles with the bound selected population then are allowed to preferentially settle in the sample and the supernatant including an enriched population is separated from the particles with the selected population bound thereto. The enriched populations in the biological sample supernatant can be further enriched by multiple removal steps.
REFERENCES:
patent: 3928143 (1975-12-01), Coughlin et al.
patent: 4016293 (1977-04-01), Coughlin et al.
patent: 4048018 (1977-09-01), Coughlin et al.
patent: 4115535 (1978-09-01), Giaever
patent: 4487700 (1984-12-01), Kanter
patent: 4788136 (1988-11-01), Grenier et al.
patent: 4910148 (1990-03-01), Sorensen et al.
patent: 5125737 (1992-06-01), Rodriguez et al.
patent: 5229268 (1993-07-01), Pry et al.
patent: 5238812 (1993-08-01), Coulter et al.
patent: 5256532 (1993-10-01), Melnicoff et al.
patent: 5576185 (1996-11-01), Coulter et al.
patent: 0 119 692 (1984-09-01), None
patent: 90/13013 (1990-11-01), None
patent: 95/28643 (1995-10-01), None
Falkenburg et al. (1986) Selective emoval of Clonogenic Neoplastic B Cells from Human Bone marrow Using Anti-HLA-DQ Antibodies and Complement. Exp. Hematol. 14. 101-107, 1986.*
Patel et al. (1993) Use of density pertubation to isolate immunologically distinct populations of cells. J. of Immunological Methods. 163. 241-251, 1993.*
Kessler et al. (1987) Large-Scale Purification and Characterization of CD34-Positive Hematopoietic Progenitor Cells. Blood. 70. Supp. 1, 1987.*
Reynolds et al. (1986) Model System for Removing Neublastoma cells from Bovine Marrow Using Monoclonal Antibodies and Magnetic Immunobeads. Cancer Research. 46. 5882-5886, 1986.*
Patel et al., “Use of density perturbation to isolate immunologically distinct populations of cells,”Journal of Immunological Methods, vol. 163, pp. 241-251 (1993).*
Reynolds, “Model System for Removing Neurblastoma Cells from Bone Marrow Using Monoclonal Antibodies and Magnetic Immunobeads,”Cancer Research, vol. 46, pp. 5882-5886 (1986).
Coulter Wallace H.
Russell Thomas R.
Schmittling Robert J.
Zwerner Robert K.
Hines J.
Miltenyi Biotec GmbH
Olstein Elliot M.
Smith Lynette R. F.
Stauffer Raymond E.
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