Method of selecting marker molecules for prediction of...

Details Method of selecting marker molecules for prediction of... Method of selecting marker molecules for prediction of...

2006-12-05

2006-12-05

Moran, Marjorie A. (Department: 1631)

Data processing: measuring, calibrating, or testing

Measurement system in a specific environment

Biological or biochemical

C703S002000, C703S011000, C702S027000

Reexamination Certificate

active

07146278

ABSTRACT:
A method predicts at least one property of a candidate molecule. A set of reference molecules is classified as either possessing or not possessing at least one property. A subset of the molecules is selected from which a plurality of marker molecules is chosen. The marker molecules are used to predict whether the candidate molecule possesses at least one property.

REFERENCES:
patent: 6434542 (2002-08-01), Farman et al.
patent: 2003/0611186 (2003-03-01), Farman et al.
patent: WO 98/47087 (1998-10-01), None
patent: WO 00/62251 (2000-10-01), None
Stanton, et al.;J. Chem. Inf. Comput. Sci., vol. 39, No. 1, 1999; “Application of Nearest-Neighbor and Cluster Analyses in Pharmaceutical Lead Discovery,” pp. 21-27.
Ghuloum, et al.,J. Med. Chem., vol. 42, No. 10, 1999, “Molecular Hashkeys: A Novel Method for Molecular Characterization and Its Application for Predicting Important Pharmaceutical Properties of Molecules,” pp. 1739-1748.
Brown, et al.,J. Chem. Inf. Comput. Sci., vol. 36, No. 3, 1996, “Use of Structure-Activity Data To Compare Structure-Based Clustering Methods and Descriptiors for Use in Compound Selection,” pp. 572-584.
Dixon, et al., “One-dimensional molecular representations and similarity calculations: methodology and validation”, J. Med. Chem., vol. 44, pp. 3795-3809, (2001).
Saiakhov, et al., “Multiple computer-automated structure evaluation model of the plasma protein binding affinity of divers drugs”, Perspectives in Drug Discovery and Designs, vol. 19, pp. 133-155, (2000).

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