Method of screening for modulators of amyloid formation

Details Method of screening for modulators of amyloid formation Method of screening for modulators of amyloid formation

1993-05-26

1994-09-20

Nutter, Nathan M.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514453, 514468, 514510, 514691, 514729, 514739, 514766, 206569, 424 2, A01N 4316, A01N 4342, A61K 3147

Patent

active

053489632

ABSTRACT:
Agents which modulate or affect the intracellular trafficking and processing of proteins in the mammalian cell can be utilized to affect the trafficking and processing of APP, thereby inhibiting production of Alzheimer type amyloidosis. Particularly useful agents are chloroquine and its related derivatives such as primaquine.

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