Method of screening for inhibitors of osteopontin

Details Method of screening for inhibitors of osteopontin Method of screening for inhibitors of osteopontin

2006-06-22

2010-02-16

Nashed, Nashaat T (Department: 1656)

Chemistry: analytical and immunological testing

Peptide, protein or amino acid

C530S329000

Reexamination Certificate

active

07662633

ABSTRACT:
Amino acids 136 to 142 and amino acids 162 to 168 of human osteopontin constitute two sites at which osteopontin interacts with α4 integrins. Products capable of disrupting those interactions are useful in therapy, particularly in the treatment of inflammatory diseases.

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