Chemistry: analytical and immunological testing – Including sample preparation – Liberation or purification of sample or separation of...
Patent
1990-10-25
1992-01-07
Lacey, David L.
Chemistry: analytical and immunological testing
Including sample preparation
Liberation or purification of sample or separation of...
422 58, 422100, 422101, 436177, 436180, 210767, 210504, 210505, G01N 3316, G01N 33551, A61K 4300, B01L 302
Patent
active
050791702
ABSTRACT:
A sample applicator for use in performing immunoassays comprises a tube defining an internal lumen and having a filter matrix at one end thereof. Sample is drawn into the applicator tube, either using a vacuum bulb or an automated assay device. The sample is filtered as it enters the tube, and is again filtered as it discharged from the tube in the opposite flow direction. By removing particulates from the liquid sample, assay performance can be greatly improved. The applicator may also comprise a reagent dispersed within a permeable matrix, which is useful for introducing reagent to a sample or other liquid assay component. As a liquid assay component is drawn into the applicator tube, the reagent is reconstituted by and mixed with the liquid, thereby reducing the number of steps required for the assay.
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Testpack Assay System, Abbott Laboratories, North Chicago, Ill.
Ascani Gary A.
Mortensen Richard B.
Rosman Daniel B.
Rundle Douglas D.
Tom Henry
Lacey David L.
Quidel Corporation
Trautman Kimberly A.
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