Method of reusing DNA-immobilization substrate

Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives

Reexamination Certificate

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C536S026420, C536S025410, C536S025400, C536S023100

Reexamination Certificate

active

07078517

ABSTRACT:
It is intended to provide a method of reusing a DNA-immobilization substrate whereby the expensive DNA-immobilization substrate can be efficiently utilized and a reusable DNA-immobilization substrate having the same performance as a new product without any trouble in practical use can be provided. Namely, a method of reusing a DNA-immobilization substrate characterized in that, to remove DNA from a DNA-immobilization substrate carrying the DNA immobilized by an acid-amide bond via an oligonucleotide to thereby enable the immobilization of a fresh DNA, the acid-amide bond between the substrate and the DNA is hydrolyzed with an acid or an alkali.

REFERENCES:
patent: 6043353 (2000-03-01), Pon et al.
patent: 2004/0209269 (2004-10-01), Dugas et al.
patent: WO 97/23496 (1997-07-01), None

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