Method of relieving inflammation by using 5-alkylsulfonylsalicyl

Details Method of relieving inflammation by using 5-alkylsulfonylsalicyl Method of relieving inflammation by using 5-alkylsulfonylsalicyl

1997-11-04

1999-09-28

Spivack, Phyllis G.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Ortho-hydroxybenzoic acid or derivative doai

A61K 31615

Patent

active

059589116

ABSTRACT:
A method of treating inflammation in a mammal, which comprises contacting the affected area with an amount sufficient to ameliorate the inflammatory condition, of a compound of the following formula ##STR1## in a pharmaceutically acceptable carrier containing a detergent, where Z is a substituted phenyl, R is a substituted or unsubstituted alkylsulfonyl group from 1 to 20 carbon atoms and X is --CN, --NO.sub.2, --H, halogen, lower alkyl or lower haloalkyl radical.

REFERENCES:
patent: 4287191 (1981-09-01), Coburn et al.
patent: 4358443 (1982-11-01), Coburn et al.
patent: 4742083 (1988-05-01), Ritchey
patent: 4939132 (1990-07-01), Coburn et al.
patent: 5240696 (1993-08-01), Van Der Ouderaa et al.
Clark et al., J. Med. Chem., 29(1) pp. 25-29.

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