Method of relieving chronic inflammation by using 5-alkylsulfony

Details Method of relieving chronic inflammation by using 5-alkylsulfony Method of relieving chronic inflammation by using 5-alkylsulfony

1999-09-28

2000-09-12

Spivack, Phyllis G.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Ortho-hydroxybenzoic acid or derivative doai

A61K 3163

Patent

active

061178594

ABSTRACT:
A method of treating chronic inflammation in a mammal is disclosed which comprises contacting the affected area with an amount sufficient to ameliorate the inflammatory condition, of a compound of the following formula: ##STR1## wherein Z is a substituted phenyl ring, R is an alkylsulfonyl group of 1-20 carbon atoms, and X is selected from the group consisting of --CN, --NO.sub.2, --H, halogen, lower alkyl and lower haloalkyl.

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patent: 4742083 (1988-05-01), Ritchey
patent: 4939132 (1990-07-01), Coburn et al.
patent: 5240696 (1993-08-01), Van Der Ouderaa et al.
Clark et al., J. Med. Chem., 29(1) pp. 25-29 (1986).

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