Method of regulation of bacterial persister status

Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives

Reexamination Certificate

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Details

C424S009100, C424S009200, C435S183000, C435S440000, C435S441000, C435S446000, C435S471000, C536S023100

Reexamination Certificate

active

07572903

ABSTRACT:
In one embodiment, the present invention is a method of controlling persister status in a bacterial cell population comprising the step of modulating the expression of native chromosomal sequences disclosed in Table 8.

REFERENCES:
Gilbert P, et al., “The physiology and collective recalcitrance of microbial biofilm communities,” Adv. Microb. Physiol. 46:202-256 (2002).
Keren I, et al., “Persister cells and tolerance to antimicrobials,” FEMS Microbiol. Lett. 230:13-18 (2004).

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