Method of reducing the undesirable gastrointestinal effects of p

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...

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Details

424273P, 424274, 424305, 424317, A61K 3161, A61K 31215, A61K 3119

Patent

active

040617424

ABSTRACT:
There is disclosed concomitant systemic administration of certain prostaglandins of the PGE-type and PGA-type, for example, 16,16-dimethyl-PGE.sub.2 of 16,16-dimethyl-PGA.sub.2, and a prostaglandin synthetase inhibitor, for example, indomethacin, aspirin, or phenylbutazone, to mammals, including humans. Thereby the undesirable gastrointestinal effects of the synthetase inhibitor are reduced.

REFERENCES:
patent: 3927213 (1976-02-01), Lippmann

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