Method of reducing subcutaneous inflammation by the topical appl

Drug – bio-affecting and body treating compositions – Effervescent or pressurized fluid containing – Organic pressurized fluid

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514568, 514570, A61K 912

Patent

active

056185162

ABSTRACT:
A hydrophile pharmaceutical composition in the form of foam is described which contains as active ingredient Ketoprofen lysine salt having a concentration between 10 and 20% p/volume of solution which allows, for topic treatment, the maximum absorption of the active principle. The foam is applied for the local treatment in painful and phlogistic conditions, of rheumatic or traumatic nature, of the articulations, of the musles, of the tendons and of the ligaments.

REFERENCES:
patent: 4282216 (1981-08-01), Rovee et al.
patent: 4593044 (1986-06-01), Metz
patent: 4954332 (1990-09-01), Bissett et al.
Abstract # CA99 (24): 200431X; Pharmacokinetics of a Slow-Release Preparation of Ketoprofen Lysine in Man; Borsa et al.
Ketoprofen Penetration into Suction Skin Blister Fluid: A Comparison of Two Topical Formulations of Ketoprofen Lysine; Advances in Therapy, vol. 10 No. 2 Mar./Apr. 1993; pp. 86-94.
Farmacocinetica Di Ketoprofene Sale Di Lisina Dopo Applicazione Percutanea Della Formulazione Schiuma: Risultati Sperimentali E Clinici; Faramci vol. 16 No. 9-10/'92; pp. 1-11.

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