Method of reducing sebum on the hair and skin

Drug – bio-affecting and body treating compositions – Live hair or scalp treating compositions – Amphoteric or zwitterionic surfactant containing

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424DIG4, 424 47, 424 59, 424 60, 424 65, 424 67, 424 68, 424 69, 514770, 514784, 514778, 514769, 514387, 514781, 514846, A61K 706, A61K 707, A61K 3142

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active

045295875

ABSTRACT:
A cosmetically acceptable composition for topical application to human skin or hair in order to reduce greasiness comprises, at a concentration of from 0.0001M to 0.5M, a biotin antagonist which is capable of blocking the activity of the biotin dependent enzyme acetyl-SCoA-carboxylase implicated in sebum production; together with a carrier other than water as an aid to delivering the biotin antagonist to the sebaceous gland.

REFERENCES:
patent: 2370662 (1945-03-01), Hertz et al.
patent: 3879534 (1975-04-01), Rambacher et al.
patent: 4243655 (1981-01-01), Gunther
Vanderwyke et al., J. Soc. Cos. Chemists, 9/1967, vol. 18, pp. 629-639.

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