Chemistry: molecular biology and microbiology – Process of mutation – cell fusion – or genetic modification – Introduction of a polynucleotide molecule into or...
Reexamination Certificate
2007-03-20
2007-03-20
Priebe, Scott D. (Department: 1633)
Chemistry: molecular biology and microbiology
Process of mutation, cell fusion, or genetic modification
Introduction of a polynucleotide molecule into or...
C435S320100, C435S325000, C435S348000, C435S375000
Reexamination Certificate
active
10438753
ABSTRACT:
Methods of reducing the excitability of an excitable cell by transforming an excitable cell with a nucleic acid construct encoding an open rectifier K+channel (dORK) (SEQ ID NO:2) or a modified open rectifier K+channel (dORKΔ) (SEQ ID NO:4), and expressing the open rectifier K+channel in the excitable cell, wherein the excitability of the transformed cell is reduced. Also featured are transgenic animals expressing dORK or dORKΔ.
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Blau Justin
Goldstein Steven A. N.
Holmes Todd C.
Nitabach Michael N.
Klauber & Jackson
New York University
Priebe Scott D.
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