Method of reducing mammalian fertility and drugs therefor

Details Method of reducing mammalian fertility and drugs therefor Method of reducing mammalian fertility and drugs therefor

1976-09-01

1978-03-28

Phillips, Delbert R.

Drug, bio-affecting and body treating compositions

Immunoglobulin, antiserum, antibody, or antibody fragment,...

Reduced antigenicity, reduced ability to bind complement, or...

2601125LH, A61K 3700, C07C10352

Patent

active

040815331

ABSTRACT:
The pre-ovulatory surge of luteinizing hormone from the pituitary gland is selectively suppressed or eliminated by introducing nonapeptide, 8-arginine vasotocin, or the tripeptide, propyl-arginyl-glycinamide, into the subject. Analogs and related peptides also exhibit a similar inhibitory effect. This anovulatory effect in the female, or reduction in spermatogenesis in the male, results in loss of fertility.

REFERENCES:
patent: 3883498 (1975-05-01), Gillessen et al.
patent: 3915947 (1975-10-01), Shields

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