Method of reducing background in fluoresence detection

Details Method of reducing background in fluoresence detection Method of reducing background in fluoresence detection

2007-06-26

2007-06-26

Riley, Jezia (Department: 1637)

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving nucleic acid

C435S112000, C562S400000, C562S575000

Reexamination Certificate

active

10179395

ABSTRACT:
The present invention provides a method for detecting fluorescence by using a solid support to which a probe molecule to be detected is fixed, wherein background is reduced by using a quenching agent. By using present invention, detection sensitivity of a DNA chip can be increased and stable data can be obtained.

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Patrick O. Brown et al.; Genome Research; vol. 6, pp. 639-645, 1996.
Richard A. Cardullo et al.; Proc. Natl. Acad. Sci., vol. 85, pp. 8790-8794, 1988.
Molecular Cloning: Appendix A1.14-A1.16, Jan. 15, 2001.

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