Drug – bio-affecting and body treating compositions – Immune response affecting drug
Patent
1995-02-24
1999-02-16
Chambers, Jasemine C.
Drug, bio-affecting and body treating compositions
Immune response affecting drug
424 852, 424 855, 4241541, 4242331, 424 932, 424 936, 514 49, 514 50, 514 44, 4353201, 435 691, A61K 3800, A61K 3820, A61K 3821, A61K 39235
Patent
active
058721541
ABSTRACT:
A method of reducing an immune response to a recombinant adenovirus which involves co-administration of the recombinant adenovirus and a selected immune modulator. The immune modulator functions by inhibiting the formation of neutralizing antibodies and/or reducing CTL killing of the virally infected cells. The method additionally encompasses the step of re-administering the recombinant adenovirus.
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Trinchieri Giorgio
Wilson James M.
Yang Yiping
Chambers Jasemine C.
Schmuck Jill
The Trustees of the University of Pennsylvania
The Wistar Institute of Anatomy & Biology
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