Method of reducing a schiff base

Details Method of reducing a schiff base Method of reducing a schiff base

1997-08-15

1998-12-08

Lee, Howard C.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

536 179, 536 185, 536 187, 536102, 536112, 5361231, 564123, 564488, 564489, C08B 3000, C08B 3700, C08B 3702, C07C20900

Patent

active

058471103

ABSTRACT:
The invention relates to methods of reducing Schiff bases and making chelator conjugates by treating with borane-pyridine complex.

REFERENCES:
patent: 3706633 (1972-12-01), Katchalski et al.
patent: 4217338 (1980-08-01), Quash
patent: 4419444 (1983-12-01), Quash
patent: 4699784 (1987-10-01), Shih et al.
patent: 4975533 (1990-12-01), Kondo et al.
patent: 5057313 (1991-10-01), Shih et al.
Pelter, A. et al., "Reductive Aminations of Ketones and Aldehydes using Borane-Pyridine", J. Chem. Soc., Perkins Trans. 1, pp. 717-720 (1984).

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