Method of recovering shiga-like toxins and vaccines comprising i

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...

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435 737, 436527, 436541, 536 53, 536124, 530413, 4242411, G01N 3353

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058887504

ABSTRACT:
Disclosed are methods of purifying shiga-like toxins (SLTs) from Polymyxin B sulfate extracts of Verotoxin-producing Escherichia coli. The methods are facile, efficient and reproducible. In another aspect, the toxin is inactivated for use in a vaccine against SLT mediated disease conditions.

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