Drug – bio-affecting and body treating compositions – Lymphokine
Patent
1979-12-18
1982-06-01
Rose, Shep K.
Drug, bio-affecting and body treating compositions
Lymphokine
A61K 3912
Patent
active
043327931
ABSTRACT:
Disclosed is a vaccine which prevents disease caused by Feline leukemia virus (FeLV) and which comprises a protease enzyme-inhibited, cell-free, ostensibly virus-free, in vitro produced feline leukemia neoantigens including FOCMA which evokes an immune response in cats by the appearance of antibodies thereto and a FeLV virion gp70 neoantigen which evokes an immune response in cats by the appearance of antibodies thereto. A novel method for making the vaccine is disclosed also.
REFERENCES:
patent: 4086134 (1978-04-01), Jarrett et al.
G. I. Ilyin; Patologicheskaia Fiziologiia i Eksperimental nava Terapiya; 1978; 16-19.
V. Kalaydjiev et al.; Proteases and Antiproteases in Cardioangiology, Int'l. Symposium, Vietri Sul Mare; 1969 (1970); 207-216.
Arora Diss. Abstr. Int. B Sci. Eng., vol 40/03, p. 1114, Ph.D, 1978 MSU Role of Protease Inhibitors in the Regulation of the Immune Response.
Richard G. Olsen et al.; California Veterinarian; Mar. 1980; 11-13.
A. I. Volosivets et al.; Profilaktika Osobo Opasnykh Infektsii Saratov.; 94-98.
Gulyy et al., Molekulyarnaya Biologiya (10):104-105 (1974), Enzyme Inhibitors and the Immune Response in Animals, USPTO Translation.
E. V. Vlasova; Biulleten Eksperimental' Noi Biologii Meditsiny; 1969; 41-43.
Melinda J. Tarr et al.; Chemico-Biological Interactions; Dec. 1979; 181-199.
Olsen, R. G. et al., Feline Practice 9(4):16-18, Jul.-Aug. 1979, Immuno Prevention of Feline Luekemia.
Ingeburg E. Goetz et al; Cancer Research; 1972; 2469-2474.
Mathes, L. E. et al., Cancer Research 39(3):950-955, Mar. 1979, Immuno Suppressive Properties of a Virion Polypeptide, A 15,000-Dalton Protein from Feline Leukemia Virus.
Hebebrande, L. C. et al., Cancer Research 39(2 Pt.1):443-447, Feb. 1979, Inhibition of Human Lymphocyte Mitogen and Antigen Response by a 15,000 Dalton Protein from Feline Leukemia Virus.
Log, T. et al., Immunol. Methods 26:291-303 (1979), Enzyme Immuno Assay for FOCMA and Detection of FOCMA in Cell Extract by Enzyme Immuno Assay Inhibition Test, C.A. 92:278W, 12748
(1980) 90:70408W, 5287
, 115352s, 16194k (1979) 89:71022g, 36770c, 1231427 (1978), C.A. 88:69685m, 58400p, 48921v (1978) 86:133639n (1977) 85:56679a (1976) 82:332c (1975) 80:2063y (1974), C.A. 79:61449f (1973) 78:93115q (1973) 77:401w, 83735g (1972) 70:18482p (1969).
Jarrett, "The Development of Vaccines Against Feline Leukemia", Origins of Human Cancer, pp. 1215-1222 (1977).
Wolff et al., Journal of Immunological Methods, 26:151-156 (1979), Recovery of Soluble Feline Oncornavirus-Associated Cell Membrane Antigen From Large Volumes of Tissue Culture Fluids.
Richard G. Olsen et al.; in Vitro; 1976; 37-43.
Linda H. Wolff et al.; J. Natl. Cancer Inst.; Mar. 1977; 791-793.
Richard G. Olsen et al.; Cancer Research; Jul. 1977; 2082-2085.
Abraham Pinter et al.; Virology; 1977; 417-422.
Abraham Pinter et al.; Virology; 1978; 345-351.
Abraham Pinter et al.; Journal of Virology; Apr. 1979; 157-165.
Dres. J. W. Diaz et al.; Revista Cubana de Farmacia; 1978; 235-242.
T. Giraldi et al.; European Journal of Cancer, Oxford.; 1977; 1321-1323.
D. J. Tweedie et al.; Biomedicine Express (see Biomedicine); 1978; 1-3.
R. Verloes et al.; Archives Internationales de Physiologie et de Biochimie Liege; 1976; 1119-1120.
A. Lupulescue; Experientia; 1980; 247-249.
A. Lage et al.; Neoplasma; 1978; 257-259.
A. L. Latner et al.; Experimental Cell Biology.; 1979; 392-400.
Giuseppe Solarino; Tumori, Milan; 1967; 103-109.
A. L. Latner et al.; British Journal of Cancer London; 1976; 535-538.
A. L. Latner et al.; Mikrobiologichnyi Zhurnal Kiev.; 1977; 751-end.
Gabriella Bamba et al.; Thrombosis Research; 1980; 41-53.
W. Troll et al.; Gesellschaft fuer Biologishe Chemie. Colliquium; 1979; 165-170.
A. W. Thomson et al.; British Journal of Cancer, London; 1977; 454-460.
Vl. Kalaydjiev et al.; Zeitschrift fuer Immunitaetshforschung, Allergie und Klinische. Immunologie, Stutgart; 1968; 98-103.
A. L. Latner et al.; British Journal of Cancer; 1974; 60-67.
A.
The invention described herein was made in the course of work under a grant or award from the Department of Health, Education and Welfare.
Rose Shep K.
The Ohio State University Research Foundation
LandOfFree
Method of recovering cell antigen and preparation of feline leuk does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Method of recovering cell antigen and preparation of feline leuk, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method of recovering cell antigen and preparation of feline leuk will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1849446