Organic compounds -- part of the class 532-570 series – Organic compounds – Carboxylic acid esters
Reexamination Certificate
2006-10-06
2011-11-29
Zucker, Paul A (Department: 1621)
Organic compounds -- part of the class 532-570 series
Organic compounds
Carboxylic acid esters
C568S364000, C568S875000, C585S601000
Reexamination Certificate
active
08067631
ABSTRACT:
To provide a method of rapid methylation of alkenes, which is applicable to the preparation of a PET tracer and which enables alkenes to be methylated through cross coupling between SP2(alkenyl) and SP3(alkyl) carbon atoms rapidly and in a high yield. Methyl iodide and an alkenyltrialkylstannane are subjected to cross coupling in an aprotic polar solvent in the presence of a palladium complex having a valence of 0, a phosphine ligand, a cuprous halide, and a carbonate and/or alkali metal fluoride.
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Hosoya Takamitsu
Suzuki Masa-aki
Gifu University
Milczarek-Desai Gavin J.
Quarles & Brady LLP
Zucker Paul A
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