Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Patent
1987-11-05
1995-05-02
Nucker, Christine M.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
435 71, 435212, 43524027, 4351722, 5303871, 530413, G01N 3353
Patent
active
054118646
ABSTRACT:
A method for purifying a recombinant protein, e.g. human tissue plasminogen activator (t-PA) from a corresponding endogenous protein of the host cell, e.g. Chinese hamster t-PA, is disclosed. The method comprises contacting a fluid containing the recombinant protein with antibodies specifically binding the corresponding endogenous protein. Monoclonal antibodies directed against and an assay for Chinese hamster t-PA are also disclosed.
REFERENCES:
patent: 4568488 (1986-02-01), Lee-Huang
B. D. Davis et al, Microbiology, Third Edition, Harper & Row Publishers, 1980, pp. 525 and 527.
Kohler et al, Nature vol. 256, Aug. 7, 1975, pp. 495-497., "Continuous Cultures Of Fused Cells Secreting Antibody Of Predefined Specificity".
Sevier, et al., Clin. Chem 27/11, 1981, pp. 1797-1806, "Monoclonal Antibodies In Clinical Immunology".
Cajot et al., Thrombosis Research 46, 141 (1987).
Matsuo et al., Thrombosis Research 36, 517 (1984).
Reagan et al, Hybridoma 4, 83 (1985); Thrombosis Research 40, 1 (1985).
Verheijen et al., The EMBO Journal 5, 3525 (1986).
Anicetti Vincent R.
Builder Stuart E.
Marks Billie J.
Ogez John R.
Patzer Eric J.
Dreger Walter H.
Genentech Inc.
Nucker Christine M.
Scheiner Laurie
LandOfFree
Method of purifying recombinant proteins from corresponding host does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Method of purifying recombinant proteins from corresponding host, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method of purifying recombinant proteins from corresponding host will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1136068