Method of purifying cyclitols

Details Method of purifying cyclitols Method of purifying cyclitols

1990-12-20

1997-05-06

Gitomer, Ralph J.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Conjugate or complex

A61K 3578

Patent

active

056268475

ABSTRACT:
A method of purifying cyclitols, particularly inositol, from mixtures including simple and complex carbohydrates begins by reducing the concentration of carbohydrates other than cyclitols to facilitate separation and crystallization of the cyclitol in high purity. Other carbohydrates can be removed or depleted from a mixture by adding a microorganism to the mixture which preferentially consumes carbohydrates but not cyclitol.

REFERENCES:
patent: 4356262 (1982-10-01), Heady
patent: 5064762 (1991-11-01), Rabinowitz
Greenberg M.L. Regulatory Mutations of Inositol Biosynthesis in Yeast: . . . , Genetics 100 19-33, 1982.
Reed, Gerald, Prescott & Donn's Industrial Microbiology 4th Ed AVI Pub, Westport CT 1982, pp. 436-437.
Demain, Arnold, Biology of Industrial Microorganisms 1985, Benjamin/Cummings Pub Co. Calif. 517-21.

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