Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Separation or purification
Patent
1997-03-20
1999-06-15
Mertz, Prema
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Separation or purification
530325, 530414, 530416, 530417, 530419, 530420, 435 695, 435 712, 435471, 4352523, 4353201, C07K 116, C07K 130, C07K 134, C07K 136
Patent
active
059123273
ABSTRACT:
The present invention relates to processes for the purification of proteins. More specifically, methods for solubilizing and purifying proteins expressed in an insoluble form using low concentrations of chaotropic agents, such as guanidine salts, are provided. Also provided are methods for refolding proteins solubilized according to the present invention.
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Gentz Reiner L.
Li Yuling
Oelkuct Mark
Human Genome Sciences Inc.
Mertz Prema
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