Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector
Reexamination Certificate
2006-01-31
2006-01-31
Smith, Lynette R. F. (Department: 1645)
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
C435S317100, C424S234100, C424S252100
Reexamination Certificate
active
06991793
ABSTRACT:
Safe and effective live vaccines againstFlavobacterium columnareof fish were created through the induction of rifampicin resistance in a nativeFlavobacterium columnareisolate; these including rifampicin-resistant mutants NRRL B-30303 and B-30304. Single immersion exposure of fish stimulated acquired immunity against virulentF. columnareinfection.
REFERENCES:
patent: 5284653 (1994-02-01), Wolf-Watz et al.
Bader, J. et al, Comparison of whole-cell antigens of pressure and formalin-killedFlexibacter columnarisfrom channel catfish (Ictalurus punctatus, Am J Vet Res, 1997; 58(9): 985-988.
Klesius, P. et al, Effect of feed deprivation on innate resistance and antibody response toFlavobacterium columnarein channel catfish, Ictalurus punctatus, Bulletin European Association of Fish Pathologist, 1999; 19(4): 156-8.
Decostere, S. et al, Shieh medium supplemented with tobramycin for selective isolation ofFlavobacterium columnare(Flexibacter columnaris) from diseased fish, Journal of Clinical Microbiology, 1997; 35(1): 322-24.
Evans Joyce J.
Klesius Phillip H.
Shoemaker Craig A.
Fado John D.
Ribando Curtis P.
Shaw Lesley
Smith Lynette R. F.
The United States of America as represented by the Secretary of
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