Method of production of optically active halohydrocarbons...

Details Method of production of optically active halohydrocarbons... Method of production of optically active halohydrocarbons...

2007-08-24

2009-12-15

Fronda, Christian L (Department: 1652)

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Preparing hydrocarbon

C435S155000, C435S183000, C435S195000

Reexamination Certificate

active

07632666

ABSTRACT:
A method of production of optically active compounds, particularly halohydrocarbons, haloalcohols, alcohols, halopolyols and polyols using hydrolytic dehalogenation of racemic or prochiral halegenhydrocarbons by dehalohenation catalysed by haloalkane dehalogenases (the enzyme code number EC 3.8.1.5) where at least one wild type or modified haloalkane dehalogenase is applied to at least one racemic or prochiral chlorinated, brominated or iodinated compound at the temperature ranged between +10 and +70° C. and pH value between 4.0 and 12.0, in aqueous system or in a monophasic organic solution or in a monophasic organic/aqueous solution or in organic/aqueous biphasic systems.

REFERENCES:
patent: WO 02/068583 (2002-09-01), None
patent: WO2006079295 (2006-08-01), None
Chica et al. Curr Opin Biotechnol. Aug. 2005;16(4):378-84.
Sen et al. Appl Biochem Biotechnol. Dec. 2007;143(3):212-23.
Kaneko et al. Accession P59337, Feb. 22, 2003.

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