Method of producing xenogenous antibodies using a bovine

Multicellular living organisms and unmodified parts thereof and – Method of using a transgenic nonhuman animal to manufacture...

Reexamination Certificate

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C800S015000, C800S005000, C800S006000, C800S007000, C800S008000, C800S014000, C800S021000

Reexamination Certificate

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07928285

ABSTRACT:
In general, the invention features genetically modified non-human mammals (e.g., bovines and other ungulates), and methods of making these mammals. In particular, the invention features transgenic ungulates having reduced levels of endogenous IgM heavy chain and/or prion protein.

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