Method of producing water-soluble sodium pheophorbide a

Details Method of producing water-soluble sodium pheophorbide a Method of producing water-soluble sodium pheophorbide a

1993-09-20

1995-01-03

Higel, Floyd D.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C07D48722

Patent

active

053788354

ABSTRACT:
A producing method of phosphoric a applied in medical treatment comprises dissolving sodium hydroxide in n-propyl alcohol, isopropyl alcohol or mixtures thereof so as to prepare a solution of the sodium hydroxide, dissolving the pheophorbide a in a solvent miscible with the sodium hydroxide solvent so as to prepare a solution of the pheophorbide a and dissolving the solution of the pheophorbide a in the solution of the sodium hydroxide so as to obtain sodium pheophorbide a. Thus, the water-soluble pheophorbide a can be safely used.

REFERENCES:
patent: 2274101 (1942-02-01), Snyder
patent: 3102891 (1963-09-01), Allen
patent: 4604241 (1986-08-01), Sakata et al.
patent: 4634557 (1987-01-01), Sato

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