Method of producing vitamin B12 using rhizobium cobalaminogenum

Details Method of producing vitamin B12 using rhizobium cobalaminogenum Method of producing vitamin B12 using rhizobium cobalaminogenum

1994-10-05

1996-08-13

Naff, David M.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Preparing compound containing saccharide radical

435170, 4352522, 435878, C12N 100, C12N 120, C12P 104, C12P 1942

Patent

active

055455387

ABSTRACT:
There is provided an economical, efficient and industrially useful method of producing vitamin B.sub.12 which comprises cultivating a microorganism belonging to Rhizobium cobalaminogenum FERM BP-4429 which is capable of producing vitamin B.sub.12 in a culture medium and recovering the vitamin B.sub.12. The microorganism is isolated from soil and has no formation of acids from L-arabinose. Further, there are no straight chain fatty acids 21:1 or 19:0.

REFERENCES:
Shemakhanova et al., "Selection of the active Rhizobium strains according . . .", 1970, abst.
Troitskaya et al. "Influence of Rhizobium japonicum strains and cobalt . . ." 1986, abst.
Troitskaya, "Effect of cultivation conditions of soy-bean on vitamin . . ." 1983, abst.
Rodynyuk et al., "Vitamin B-12 accumulation . . . ," 1974, abst.
Rodynuk et al., "Bgroup vit. level in nodules . . . ," 1973, abst.
Elmerich et al., "Nicotinic acid requirement and degrada-tion by Sesbania rhizobium strain ORSS71", 1983, 281-84.
Abstract from obraz. Fiziol. AKT. Veshchestv Mikroorg., 1975 Rodynyuk et al., "Role of B vit(s) & a.a. in rel. betwn. symb. bact.".
Abstract from Izobreteniya, Roslyakova et al., 1992 (21), p. 103 "Improving growth of Rhizobium in . . .".
Chanova, "Release Of Vitamin B12 From Rh. Leguminosarum", Chemical Abstracts, vol. 89, No. 15, Oct. 9, 1978, p. 294, left column, No. 125 899u.
Samtsevich et al., "Production of Vitamin B12 By Rhizobial Bacteria Of Lupine", Chemical Abstracts, vol. 85, No. 17, Oct. 25, 1976, p. 279, left column, No. 119 366u.
Leiderman et al., "Vitamin B12 Synthesis By Rhizobium Phaseoli", Chemical Abstracts, vol. 82, No. 19, May 12, 1975, p. 251, right column, No. 121 470e.
KLIEWER et al., "Cobamide Coenzyme Contents of Soybean Nodules & Nitrogen Fixing Bacteria in Relation to Physiological Conditions", Plant Physiology, 38, 99-104 (1963).

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