Method of producing vaccines

Details Method of producing vaccines Method of producing vaccines

1976-09-02

1978-01-31

Rosen, Sam

Drug, bio-affecting and body treating compositions

Whole live micro-organism, cell, or virus containing

Genetically modified micro-organism, cell, or virus

195 15, 424 89, A61K 4100, A61K 3912, C12K 700

Patent

active

040716198

ABSTRACT:
A method for producing vaccines wherein a suspension of the viral culture is purified by gel chromatography in a column packed with a porous virion non-sorbing silicate material having pore diameter of 50 to 10000 A, followed by adsorption-elution concentration and completion of the vaccine, or the starting suspension of the viral culture is concentrated by adsorption-elution and then purified by gel chromatography in a column packed with porous silicate material having pore diameter of 50 to 10000 A, or the starting suspension of the viral culture is subjected to gel chromatography in a column filled with a porous silicate material having pore diameter of 50 to 10000 A and the final vaccine is produced.

REFERENCES:
haller - Nature - vol. 204 (May 15,1965) pp. 693-696.

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