Method of producing transglutaminase having broad substrate...

Chemistry: molecular biology and microbiology – Enzyme – proenzyme; compositions thereof; process for... – Transferase other than ribonuclease

Reexamination Certificate

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C435S252300, C435S320100, C435S886000, C536S023200, C530S350000

Reexamination Certificate

active

07101695

ABSTRACT:
Embodiments of the invention generally provide methods and compositions for producing recombinant transglutaminases. The purified recombinant transglutaminases of the invention are reactive to a broad range of compounds and exhibit broad substrate activity. In one embodiment,Streptoverticillium mobaraense(ATCC 29032), andStreptoverticillium cinnamoneum(ATCC 11874) recombinant transglutaminase fusion proteins purified fromE. coliare provided to a better yield, higher purity, and activity than hitherto possible by recombinant DNA technology.

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