Method of producing sustained-release preparation

Details Method of producing sustained-release preparation Method of producing sustained-release preparation

1994-07-05

1996-07-09

Nutter, Nathan M.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Particulate form

424 854, 424484, 514 2, 514 21, 514964, A61K 914

Patent

active

055342698

ABSTRACT:
A method of producing a sustained-release preparation which includes permitting a water-soluble polypeptide to permeate into a biodegradable matrix in the aqueous solution. The production method of the present invention makes possible the permeation of a water-soluble polypeptide into a biodegradable matrix without bringing the water-soluble polypeptide into contact with an organic solvent. Hence the water-soluble polypeptide is prepared without affecting the water-soluble polypeptide bioactivity and is thus effective for use as a pharmaceutical.

REFERENCES:
patent: 4962091 (1990-10-01), Eppstein et al.
A. Supersaxo et al., "Preformed porous microspheres for controlled and pulsed release of macro-molecules", Journal of Controlled Release, vol. 23, (1993), pp. 157-164.

Affiliated with

Also associated with

Rating

Method of producing sustained-release preparation does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Method of producing sustained-release preparation, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method of producing sustained-release preparation will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1865557