Method of producing standardized povidone iodine preparations an

Details Method of producing standardized povidone iodine preparations an Method of producing standardized povidone iodine preparations an

1988-09-22

1990-09-04

Robinson, Allen J.

Drug, bio-affecting and body treating compositions

Inorganic active ingredient containing

Elemental iodine or iodine compound

424 80, A61K 3336

Patent

active

049543512

ABSTRACT:
A pharmaceutical iodophor preparation having predictable microbicidal effectiveness and long duration of action comprising polyvinylpyrrolidone-iodine (PVPI), free iodine, a source of iodide ions and a source of iodate ions, the preparation having a ratio of available (titratable) iodine to iodide between 2:1 and 10:1, a pH between 5 and 6 and a free iodine concentration between 2 and 20 ppm, wherein the amount of iodate ion in the preparation is sufficient to maintain the free iodine concentration between 2 and 20 ppm for at least 12 months at 20.degree. C.

REFERENCES:
patent: 4271149 (1981-06-01), Winicov et al.

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