Method of producing slow-release pharmaceutical forms

Details Method of producing slow-release pharmaceutical forms Method of producing slow-release pharmaceutical forms

1986-01-21

1988-10-25

Griffin, Ronald W.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Particulate form

424 81, 424497, 514944, 514964, 514965, A61K 922, A61K 952

Patent

active

047803223

ABSTRACT:
The invention relates to a novel method of producing slow-release pharmaceutical forms administered per os, by simultaneously employing two resins having anionic character, the proportions of said resins being variable.
By varying the ratio of the amounts of active principles on the respective two resins, it is possible to modify the release kinetics of active principle; and by independently varying the amount of carboxylic resin it is possible to produce stabile pharmaceutical preparations which are in liquid, semi-liquid, or solid form.

REFERENCES:
patent: 3108044 (1963-10-01), Rety et al.
patent: 3138525 (1964-06-01), Koff
patent: 3594470 (1971-07-01), Borodkin et al.
patent: 3608063 (1971-09-01), Banker
patent: 4013820 (1977-03-01), Farhadieh et al.
patent: 4499066 (1985-02-01), Moro et al.
patent: 4514385 (1985-04-01), Damani et al.
patent: 4606909 (1986-08-01), Bechgaard et al.
patent: 4618491 (1986-10-01), Kanematu et al.
patent: 4693887 (1987-09-01), Shah

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