Method of producing single-chain Fv molecules

Details Method of producing single-chain Fv molecules Method of producing single-chain Fv molecules

1994-08-17

1999-03-30

Huff, Sheela

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Recombinant dna technique included in method of making a...

4351723, 435328, 4353201, 5303873, 4241331, A61K 39395, C07H 2104

Patent

active

058887733

ABSTRACT:
The invention relates to a method of producing single-chain Fv molecules in eukaryotic cells, and to secretable sFv proteins having at least one non-naturally occurring glycosylation site. The single-chain Fv molecules produced by this method are biologically active and capable of being secreted from eukaryotic cells into the cell culture medium.

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