Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing alpha or beta amino acid or substituted amino acid...
Patent
1996-08-09
1998-01-13
Lankford, Jr., Leon B.
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Preparing alpha or beta amino acid or substituted amino acid...
435106, C12P 1304, C12P 1306
Patent
active
057078378
ABSTRACT:
A method is disclosed by which N-carbamoyl-(R)-tert.-leucine is obtained from tert-butyl hydantoin by means of an (R)-specific hydantoinase, in which N-carbamoyl-(R)-tert.-leucine is converted by reaction with nitrite or an (R)-carbamoylase to (R)-tert-leucine.
REFERENCES:
patent: 4744990 (1988-05-01), Bragdon et al.
patent: 4871552 (1989-10-01), Bragdon et al.
patent: 5516660 (1996-05-01), Wagner et al.
Bommarius, et al., Tetrahedron: Asymmetry, (1995) "Synthesis and Use of Enantiomerically Pure Tert-Leucine", pp. 2853-2888.
Bommarius Andreas
Drauz Karlheinz
Kottenhahn Matthias
Degussa - Aktiengesellschaft
Lankford , Jr. Leon B.
Tate Christopher R.
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