Method of producing proteins with FVIII activity and/or FVIII de

Details Method of producing proteins with FVIII activity and/or FVIII de Method of producing proteins with FVIII activity and/or FVIII de

1994-10-11

1997-03-11

Ziska, Suzanne E.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Recombinant dna technique included in method of making a...

435 696, 4353201, 4351723, 530383, 536 235, C12N 1500, C12N 500, C12P 2106, C07H 2104

Patent

active

056100337

ABSTRACT:
In a process for producing proteins with FVIII activity and FVIII derivatives by in vitro culturing of mammalian cells, the culturing is carried out at temperatures below 32.degree. C. and the culturing times used are below 24 hours.

REFERENCES:
patent: 4746608 (1988-05-01), Mizukami et al.
Kaufman et al J.B.C. 263:6352, 1988.
Sebingin. CRC Certified Review Clim. Lab. Sci. 23(1):43, 1986.

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