Method of producing pantethine

Details Method of producing pantethine Method of producing pantethine

1976-08-10

1977-11-29

Demers, Arthur P.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

260561B, 260562N, C07C14923

Patent

active

040605515

ABSTRACT:
Salt of pantothenic acid and salt of cystamine or cysteamine are caused to react under the presence of an accelerator selected from the group consisting of carbodiimides and N-hydroxy compounds without any pretreatment thereby producing pantethine or pantetheine, and the pantetheine is oxidized to produce pantethine which is a precursor of co-enzyme A.

REFERENCES:
patent: 2625565 (1953-01-01), Snell et al.
patent: 2680767 (1954-01-01), Snell et al.
patent: 2680768 (1954-06-01), Snell et al.
patent: 3300508 (1967-01-01), Shimizu et al.
Ohta et al. Chem. Abstracts 64(1966) column 17710b.
Gross et al. Tetrahedron 24(1968) pp. 6935-6939.

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