Method of producing of an antimeningococcic hyperimmune gamma gl

Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Blood proteins or globulins – e.g. – proteoglycans – platelet...

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530412, 530413, 530414, 530415, 530416, 530417, 530418, 530419, 530427, 5303871, 4241301, 42419711, 4242501, 4242781, 4242791, 4242821, 424531, C07K 1612, A61K 3940, A61K 39095, A23J 320

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057476535

ABSTRACT:
A vaccine effective against infection caused by group B Nesseria meningitidis microorganism is provided which comprises a purified protein antigenic complex weighing from 65 to 95 kDa, vesicles, and capsular polysaccharides. This vaccine is extracted from the cell membranes of the live microorganisms using detergent and enzyme. The method of producing an antimeningococcic hyperimmune gammaglobulin and the gammaglobulin produced by the method was provided. The gammaglobulin is obtained from vaccinees vaccinated with the vaccine.

REFERENCES:
patent: 4451446 (1984-05-01), Vandevelde et al.
patent: 4505853 (1985-03-01), Goldstein et al.
patent: 4601903 (1986-07-01), Frasch
patent: 4629723 (1986-12-01), Goldstein et al.
Sigma Catalog, published by Sigma Chemical Company (St. Louis, MO), see p. 1192 1988.

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