Method of producing neuromuscular block by the use of tetra-prop

Details Method of producing neuromuscular block by the use of tetra-prop Method of producing neuromuscular block by the use of tetra-prop

1997-10-15

2000-02-15

Henley, III, Raymond

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Nitrogen containing other than solely as a nitrogen in an...

A61K 3114

Patent

active

060253991

ABSTRACT:
A method for inducing neuromuscular blockade is described which is based on the administration to a surgical patient of an amount of a drug comprising tetrabutylammonium or a mixture of tetrabutylammonium and tetrapropylammonium which is effective to induce a neuromuscular block. In addition, there is disclosed the method of combining a non depolarizing muscle relaxant with the tetrabutylammonium or tetraproplyammonium compound to provide a neuromuscular block which requires a reduced dosage of both drugs.

REFERENCES:
patent: 3965178 (1976-06-01), Johnson et al.
patent: 4931593 (1990-06-01), Siray et al.
patent: 4968433 (1990-11-01), Schmidt et al.

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