Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Lymphokines – e.g. – interferons – interlukins – etc.
Patent
1986-06-05
1988-02-02
Phillips, Delbert R.
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Lymphokines, e.g., interferons, interlukins, etc.
530350, 530380, 530829, 530830, C07G 702, A61K 3514, A61K 3704
Patent
active
047229985
ABSTRACT:
The present invention is directed to a method of producing growth factors for mammalian cells. More particularly, the method of the present invention comprises isolating mammalian inducer T-lymphocytes, and stimulating growth factor production by contacting these inducer lymphocytes with an antigen or a mitogen. The resulting growth factors are then separated from the material produced by the stimulated lymphocytes.
REFERENCES:
patent: 4390623 (1983-06-01), Frabricius et al.
patent: 4401756 (1983-08-01), Gillis
Watson et al, "Biochemical and Biological Characterization of Lymphocyte Regulatory Molecules", J. Exp. Med., vol. 15, Oct. 1979, pp. 849-861.
Cantor Harvey I.
Nabel Gary
Conlin David G.
Dana Farber Cancer Institute
Linek Ernest V.
Nutter Nathan M.
Phillips Delbert R.
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