Method of producing low molecular weight chitin/chitosan and...

Details Method of producing low molecular weight chitin/chitosan and... Method of producing low molecular weight chitin/chitosan and...

2006-11-28

2006-11-28

Maier, Leigh C. (Department: 1623)

Dentistry

Prosthodontics

Tooth construction

C424S042000, C424S042000, C514S055000, C623S023510, C623S023610

Reexamination Certificate

active

07140882

ABSTRACT:
By irradiating60Co γ ray to chitin/chitosan, chitin/chitosan having high molecular weight is separated or decomposed into low molecular weight chitin/chitosan. A method of producing an osteoconduction substance comprises the steps of irradiating60Co γ ray to chitin/chitosan to produce low molecular weight chitin/chitosan; preparing chitosan sol by dissolving low molecular weight chitin/chitosan in an acidic aqueous solution to obtain a chitosan acidic aqueous solution and kneading the chitosan acidic aqueous solution and apatite powder; and neutralizing the chitosan sol by the use of a neutralizing agent.

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C. Zahraoui et al., “Influence of Sterilization on Injectable Bone Biomaterials,”Bone(1999), 25(2):63S-65S, Elsevier Science, Inc.

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