Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Liposomes
Patent
1994-06-02
1996-07-30
Kishore, Gollamudi S.
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Liposomes
264 41, 264 43, 4284022, A61K 9127
Patent
active
055409369
ABSTRACT:
This invention provides a process for the production of liposomes by combining an organic phase and an aqueous at a volume ratio of less than 3:1; the process can be conducted under conditions which obtain a single-modal population distribution of liposomes encompassing a pre-selected mean particle size. A novel intermediate product obtained during the process, which can itself be used for the topical delivery of a bioactive agent, is also provided.
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Boni Lawrence
Coe Royden M.
Edgerly-Pflug Laura
Minchey Sharma R.
Portnoff Joel
Kishore Gollamudi S.
Rubin Kenneth B.
The Liposome Company Inc.
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