Method of producing L-isoleucine using Brevibacterium flavum

Details Method of producing L-isoleucine using Brevibacterium flavum Method of producing L-isoleucine using Brevibacterium flavum

1978-06-22

1980-12-02

Wiseman, Thomas G.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Preparing alpha or beta amino acid or substituted amino acid...

435172, 435840, C12P 1306, C12N 1500, C12R 113

Patent

active

042372283

ABSTRACT:
A method of producing L-isoleucine which comprises culturing the strain of Brevibacterium flavum VNII Genetika 10-89 deposited under the number CMIM B-1507 in a nutrient medium containing sources of nitrogen, carbon, mineral salts and vitamins and under aerobic conditions.
Said strain makes it possible to produce L-isoleucine with a yield of 17 g/l and more.

REFERENCES:
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patent: 3231478 (1966-01-01), Uemura et al.
patent: 3262861 (1966-07-01), Kinoshita et al.
patent: 3502544 (1970-03-01), Sugiskai et al.
patent: 3767529 (1973-10-01), Yoshinaga et al.
Ikeda, et al., "Screening of L-Isoleucine Producers among Ethiomine Resistant Mutants of L-Threonine Producing Bacteria", Agr. Biol. Chem., vol. 40, No. 3, (1976), pp. 511-516.
Kisumi, et al., "Isoleucine Accumulation by Regulatory Mutants of Serratia Marcescens: Lack of both Feeback Inhibition and Repression" J. Bact., vol. 110, No. 2, (1972), pp. 761-763.
Shilo, et al., "Production of L-Isoleucine by AHV Resistant Mutants of Brevibacterium flavum", Agr. Biol. Chem., vol. 37, No. 9, (1973), pp. 2053-2061.
Kase, et al., "L-Isoleucine Production by Analog-resistant Mutants Derived from Threonine-Producing Strain of Corgnebacterium glutamicam", Agr. Biol. chem., vol. 41, No. 1, (1977), pp. 109-116.

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