Method of producing Iodine-124 and meta-iodobenzylguanidine cont

Details Method of producing Iodine-124 and meta-iodobenzylguanidine cont Method of producing Iodine-124 and meta-iodobenzylguanidine cont

1989-03-02

1991-05-28

Jordan, Charles T.

Induced nuclear reactions: processes, systems, and elements

Nuclear transmutation

By charged particle bombardment

376199, G21G 110

Patent

active

050193236

ABSTRACT:
This invention relates to a method for synthesizing Iodine-124 and also a class of radiopharmaceutical which, by virtue of an Iodine-124 label, can be used for both diagnostic and therapeutic purposes. The method comprises an innovative technique for preparing an irradiation target, irradiating the prepared target, and finally collecting Iodine-124 created by the irradiation. The method of this invention provides Iodine-124 in sufficient yields and radionuclidic purity that can be used with positron emission tomography. The invention further relates to the use of Iodine-124 in a chemical form incorporated into organic and inorganic radiopharmaceuticals.

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