Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Enzymatic production of a protein or polypeptide
Patent
1979-11-20
1981-12-22
Tanenholtz, Alvin E.
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Enzymatic production of a protein or polypeptide
435811, C12P 2100
Patent
active
043071937
ABSTRACT:
In the method of the present invention for production of interferon from propagating tissue culture cells, a propagating apparatus is utilized having a plurality of spaced-apart parallel flat plates. Monolayers of the tissue cells are grown on these plates and the apparatus is adapted for the introduction of gas and/or liquid mediums between the plates. In carrying out the method of the present invention the culture medium which nourishes the propagating cell tissues is exposed to a gas phase for oxygenating and adjusting the pH of the medium, while maintaining the culture medium and the propagated cells in a static and undisturbed condition.
REFERENCES:
patent: 3773924 (1973-11-01), Ho
patent: 3843454 (1974-10-01), Weiss
patent: 3951740 (1976-04-01), Gresser et al.
patent: 4007086 (1977-02-01), Hamilton
Miller Austin R.
Tanenholtz Alvin E.
Toray Industries Inc.
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