Method of producing inosine and/or guanosine

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing compound containing saccharide radical

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4351721, 435253, 435832, 435839, C12P 1940, C12N 1500, C12N 120, C12R 107, C12R 1125

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047014130

ABSTRACT:
Method of producing inosine and/or guanosine by culturing an inosine and/or guanosine-producing mutant of the genus Bacillus which requires adenine for growth and is resistant to an antifolate. Thus, inosine and/or guanosine can be produced in much greater yields, compared with known methods.

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Lehninger, A., in Biochemistry 2d edition, Worth Publishers, Inc., pp. 345-347 & 729-735.
Kornberg (1980), DNA Replication, W. H. Freeman and Company, p. 422.
Kornberg (1982), 1982 Supplement to DNA Replication, W. H. Freeman and Company, p. S133.
Anand (1975), Antibiotics, vol. III, ed-Corcoran & Hahn, pp. 668-678.

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