Method of producing fibrin-specific monoclonal antibodies lackin

Details Method of producing fibrin-specific monoclonal antibodies lackin Method of producing fibrin-specific monoclonal antibodies lackin

1986-01-30

1990-05-22

Moskowitz, Margaret

Chemistry: natural resins or derivatives; peptides or proteins;

Proteins, i.e., more than 100 amino acid residues

Blood proteins or globulins, e.g., proteoglycans, platelet...

530382, 530380, 530329, 530806, 530807, 530808, 530809, 530812, 435 7021, 4351722, 43524027, 935 93, 935 95, 935104, 514 16, 424 858, C07K 1514, A61K 39395, I07K 1504, C12N 3500

Patent

active

049279165

ABSTRACT:
Peptides comprising fibrin-specific epitopic sequences are used to prepare hybridoma cell lines producing antifibrin-specific monoclonal antibodies substantially devoid of fibrinogen-cross-reactivity obtained by somatic cell fusion. The antibodies are useful for the in vivo and in vitro detection of thrombi and fibrin deposits.

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