Method of producing cecropins by microbiological techniques

Details Method of producing cecropins by microbiological techniques Method of producing cecropins by microbiological techniques

1991-01-03

1993-04-27

Hill, Jr., Robert J.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Recombinant dna technique included in method of making a...

4352523, 4353201, 530350, C07K 1300, C17N 1562, C17N 1563

Patent

active

052061540

ABSTRACT:
A polynucleotide molecule expressible in a given host comprising the sequence of the araB promoter operably linked to a gene which is heterologous to said host. The heterologous gene codes for a peptide that is biologically active. The invention also relates to a genetic construct which comprises a first genetic sequence coding for cecropin operably linked to a second genetic sequence coding for a polypeptide which is capable of suppressing the bactericidal effect of the resulting fusion protein towards an otherwise cecropin sensitive bacterium.

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