Method of producing carnitine

Details Method of producing carnitine Method of producing carnitine

1988-12-02

1991-08-20

Robinson, Douglas W.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Preparing nitrogen-containing organic compound

435136, 435106, 435280, 435893, C12P 1300, C12P 1340, C12P 1384

Patent

active

050413759

ABSTRACT:
This invention relates to a method for producing carnitine comprising contacting, in a reaction medium, carnitinenitrile with (A) a nitrilase capable of hydrolyzing carnitinenitrile to form carnitine or (B) a microorganism containing said nitrilase.

REFERENCES:
patent: 4001081 (1977-01-01), Commeyras
patent: 4366250 (1982-12-01), Jallageas
patent: 4371618 (1983-02-01), Cavazza
patent: 4636471 (1987-01-01), Nakamura et al.
patent: 4642290 (1987-02-01), Sih
Fujita et al., Chem. and Pharm. Bull., vol. 9, 1961 pp. 661-665.
Biotechnology and Bioengineering, vol. 26, pp. 911-915 (1984) "Chohinesterase-Catalyzed Resolution of D,L-Carnitine".
Applied and Environmental Microbiology, pp. 327-334 (1980) "Enzymatic Synthesis of L-Carnitine by Reduction of an Achiral Precursor: the Problem of Reduced Nicotinamide Adenine Dinucleotide Recycling".

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